gTranslate

gTranlate is under active development and is not yet available for public use.

gTranslate is a machine learning-based command-line tool for predicting the translation table (TT) used by prokaryotic genomes. By analyzing specific sequence features — such as coding density differences, Trp ratios, and Gly ratios — gTranslate can accurately distinguish between the genetic codes associated with reassignment of the UGA stop codon, i.e. translation tables 11 (standard prokaryotic code), 4 (UGA=Trp), and 25 (UGA=Gly).

gTranslate is open source and released under the GNU General Public License (Version 3).

Notifications about gTranslate releases will be available through the GTDB Bluesky account https://bsky.app/profile/ace-gtdb.bsky.social.

Please post questions and issues related to gTranslate on the Issues section of the GitHub repository.

Running gTranslate

  1. Install gTranslate (or use the third-party web application) (Installing gTranslate)

  2. Access the help documentation Commands, or view the program help menu: gtranslate -h

  • Note: Individual help can be accessed via the specific command, e.g.: gtranslate detect_table -h

Citing gTranslate

We encourage you to cite gTranslate and the third-party dependencies as described in References.

Running gTranslate